Long-term prognosis after childhood kidney disease

Self-limiting kidney conditions are common in children, and we expect most of those with pyelonephritis, glomerulonephritis and other glomerular diseases to make a full recovery. However, a very long-term cohort study from Israel suggests that we should not be so complacent (Calderon-Margalit R et al NEJM 2018. 10.1056/NEJMoa1700993).

In Israel, military conscription has been compulsory for many years, for all men and most women of Jewish ethnicity. All conscripts undergo a thorough medical assessment at recruitment, which affords a unique opportunity to examine the health status of the entire population. Recruiting medical officers also have access to all past medical records.

Between 1967 and 1997 over 1.5 million Israelis aged 16 to 25 years (mean 17.7) were recruited. They all underwent examination, including blood pressure measurement and urine dipstick testing. They joined the cohort only if this assessment showed no signs of kidney disease. They were then followed for a...

from Archives of Disease in Childhood current issue http://ift.tt/2psNigL